After securing his master of arts in political science from Harvard University and earning multiple fellowships, Jorge Dominguez remained at Harvard to complete his doctoral coursework and dissertation. He obtained a doctorate in political science in 1972, and his dissertation won the Harvard Government Department's Toppan Prize. Making a successful transition from Harvard student to Harvard educator, Jorge Dominguez remained with the institution for the entirety of his career, teaching courses in multiple departments as a full professor. 

Jorge Dominguez has also served in multiple administrative and mentorship roles over the course of his 46-year career at Harvard. Helping students through their dissertations, he has sat on 67 different dissertation committees and chaired an additional 39.

In addition to his work at Harvard, Mr. Dominguez has held visiting appointments with multiple institutions in the US, Mexico, and Spain. An author and editor of several books, he has also written and co-written dozens of academic articles and book chapters.